| Product | Recombinant penicillin binding protein, PBP2x, beta-lactam receptor protein |
|---|---|
| Product # | AB5022 |
| Category | Recombinant Protein |
| Tags | antibiotic, protein |
| Unit Size | 0.5 mg |
| Source | E. Coli |
| Species | N/A |
| Conjugate | Unconjugated |
| Storage | -20 degree celsius or below for long term storage. Room temperature for shipment. |
| Shelf-life | At least 12 months when stored properly. |
| Application | ELISA, lateral flow, etc. |
| Application Notes | Dilute the lyophlized product with distilled water 1mL, then determine the final dilution according to your own assay. |
PBP2x, beta-lactam receptor protein is derived from E Coli. It can be used in bioassays for the detection of beta-lactams antibiotics, including penicillin, amoxicillin, cefalotin, etc. It is highly sensitive and specific to beta-lactam groups.
Penicillin-binding proteins (PBPs) are a group of proteins that are characterized by their affinity for and binding of penicillin. They are a normal constituent of many bacteria; the name just reflects the way by which the protein was discovered. All β-lactam antibiotics (except for tabtoxinine-β-lactam, which inhibits glutamine synthetase) bind to PBPs, which are essential for bacterial cell wall synthesis. PBPs are members of a subgroup of enzymes called transpeptidases. Specifically, PBPs are DD-transpeptidases.
PBP2x belongs to PBPs and represents a primary resistance determinant for beta-lactams.
