|Product||Recombinant penicillin binding protein, PBP2x, beta-lactam receptor protein|
-20 degree celsius or below for long term storage. Room temperature for shipment.
At least 12 months when stored properly.
ELISA, lateral flow, etc.
Dilute the lyophlized product with distilled water 1mL, then determine the final dilution according to your own assay.
PBP2x, beta-lactam receptor protein is derived from E Coli. It can be used in bioassays for the detection of beta-lactams antibiotics, including penicillin, amoxicillin, cefalotin, etc. It is highly sensitive and specific to beta-lactam groups.
Penicillin-binding proteins (PBPs) are a group of proteins that are characterized by their affinity for and binding of penicillin. They are a normal constituent of many bacteria; the name just reflects the way by which the protein was discovered. All β-lactam antibiotics (except for tabtoxinine-β-lactam, which inhibits glutamine synthetase) bind to PBPs, which are essential for bacterial cell wall synthesis. PBPs are members of a subgroup of enzymes called transpeptidases. Specifically, PBPs are DD-transpeptidases.
PBP2x belongs to PBPs and represents a primary resistance determinant for beta-lactams.