Bovine Viral Diarrhea (BVD) is a disease of cattle caused by the Bovine Viral Diarrhea Virus (BVDV). The virus is widespread and most herds are at risk for infection. In the susceptible herd, BVD can be a serious, costly disease.

The signs of BVD vary, depending on the immune status of the exposed animals, and the strain of the infecting virus. The incubation period is about three to five days. If susceptible (non-vaccinated) animals are infected with a virulent strain of the virus, the disease will likely appear as an acute, severe sickness, with bloody diarrhea, high fever (105–107 degrees), off- feed, mouth ulcers, and often pneumonia. Some infected animals may die, while others will recover, usually within one or two weeks. Occasionally an animal will die very quickly, before other signs are apparent. Since BVD is a viral disease, antibiotics are ineffective.

Bovine viral diarrhea virus is the prototypic member of the genus Pestivirus within the family Flaviviridae. This Recombinant bovine viral diarrhea virus P80 protein, BVDV P80 is a recombinant protein provided in E Coli, which can be used for immunoassays such as ELISA, lateral flow assays, etc.